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Fioricet is a combination of acetaminophen, butalbital, and caffeine. Acetaminophen is an analgesic, butalbital is a barbiturate, and caffeine is a stimulant. Acetaminophen stops the production of prostaglandins, which are chemicals that cause inflammation and pain. This action reduces pain signals sent to the brain.
Butalbital is a central nervous system depressant. It works by binding to receptors in the brain that are responsible for alertness and arousal. This binding reduces the activity of these receptors, resulting in a calming effect.
Caffeine is a stimulant that raises the activity of neurons in the brain. It operates by blocking the action of adenosine, a neurotransmitter that causes drowsiness. By blocking adenosine, caffeine keeps the brain alert and active. These three components reduce pain, relax muscles, and increase alertness.