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Percocet is a prescription medication that combines two active ingredients: oxycodone, a powerful opioid pain reliever, and acetaminophen, a non-opioid pain reducer. This combination makes Percocet effective for relieving moderate to severe pain, especially when other medications such as ibuprofen or acetaminophen alone are not strong enough. Doctors may prescribe Percocet after surgery, injury, or dental procedures, or for certain chronic pain conditions when short-term opioid therapy is considered appropriate.